Our Work
SISHU covers a variety of topics in neonatal health and focuses on contextualizing evidence and creating simple workflows for clinical integration of screening. Our non-profit SISHUMed has also been designed to facilitate development of low-cost resources to support screening.
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Heart Screening
Critical Congenital Heart Disease (CCHD) affects approximately 1–2 out of every 1,000 newborns. Early screening helps detect serious heart conditions before symptoms become life-threatening. SISHU has helped provide training of CCHD screening to VMH and four rural hospitals covering a delivery rate of 4,000 newborns. SISHUMed is currently working on developing a low-cost dual-sensor pulse oximeter with clinical decision support for heart screening.
Hearing Screening
Congenital Hearing Loss affects 1–7 out of every 1,000 newborns. Early detection supports healthy speech, language, and developmental milestones. SISHU has helped provide training in proper OAE use for hearing screening. We are also partnering with University of Washington in testing a smartphone-based OAE for rural settings.
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Genetic Screening
Genetic Screening can identify over 80 inherited conditions, including sickle cell disease, congenital hypothyroidism, metabolic disorders, and endocrine conditions — allowing for earlier treatment and improved outcomes. We are currently working with Trivitron to assess feasibility of limited genetic screening through dry blood spot.
Jaundice Screening
Neonatal Jaundice affects up to 60% of newborns. Severe untreated jaundice can lead to serious and permanent neurological complications. We have partnered with Picterus Newborn Health, a company based in Norway that has designed a smartphone-based transcutaneous bilirubin monitoring using a color calibration card and camera feature. We are assessing feasibility for home-based jaundice screening programs utilizing this low-cost tool.
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Targeted Screening of at-risk Newborns
SISHU is committed to offering evidence-based management guidance and straightforward clinical decision-support for various conditions, including neonatal hypoglycemia, sepsis, and cerebral palsy. Our goal is to enhance clinical and improve patient outcomes through accessible and reliable resources.